WAPROBEN® Tablets

Robenacoxib Tablets

For Veterinary Use Only

COMPOSITION

WAPROBEN® 6

Each tablet contains:

Robenacoxib ........................................ 6 mg

Excipients ............................................. q.s.

WAPROBEN® 20

Each tablet contains:

Robenacoxib ...................................... 20 mg

Excipients ............................................. q.s.

WAPROBEN® 40

Each tablet contains:

Robenacoxib ...................................... 40 mg

Excipients ............................................. q.s.

PHARMACEUTICAL FORM

Palatable, scored oral tablets.

TARGET SPECIES

• Dogs

• Cats

INDICATIONS

WAPROBEN® is indicated for the relief of pain and inflammation associated with:

Dogs

• Osteoarthritis

• Musculoskeletal disorders

• Orthopedic surgery

• Soft tissue surgery

• Dental surgery

• Post-operative pain

Cats

• Acute musculoskeletal pain

• Soft tissue surgery

• Orthopedic surgery

• Dental procedures

PHARMACOLOGICAL PROPERTIES

Robenacoxib is a selective cyclooxygenase-2 (COX-2) inhibitor belonging to the coxib class of NSAIDs.

It provides:

• Potent anti-inflammatory activity

• Effective analgesia

• Antipyretic action

• Rapid onset of action

• Once-daily dosing

Robenacoxib preferentially accumulates in inflamed tissues while maintaining a relatively short residence time in blood.

DOSAGE AND ADMINISTRATION

Administer orally.

Dogs

1–2 mg/kg body weight once daily

Cats

1–2 mg/kg body weight once daily

Treatment duration:

• Osteoarthritis: According to clinical response.

• Post-operative pain: Up to 3–6 days, depending on the procedure and veterinary assessment.

CONTRAINDICATIONS

Do not use in:

• Animals with gastrointestinal ulceration

• Severe hepatic impairment

• Severe renal disease

• Cardiac insufficiency

• Animals hypersensitive to NSAIDs

Do not administer with corticosteroids or other NSAIDs.

SPECIAL WARNINGS

• Ensure adequate hydration before treatment.

• Monitor liver and kidney function during prolonged administration.

• Use the lowest effective dose for the shortest appropriate duration.

ADVERSE REACTIONS

Occasionally:

• Vomiting

• Diarrhea

• Reduced appetite

• Lethargy

Rarely:

• Gastrointestinal ulceration

• Renal dysfunction

• Hepatic dysfunction

• Hypersensitivity reactions

Discontinue treatment if serious adverse effects occur.

USE DURING PREGNANCY AND LACTATION

Use only according to the benefit-risk assessment of the attending veterinarian.

OVERDOSE

Overdosage may result in:

• Gastrointestinal disturbances

• Renal impairment

• Depression

• Dehydration

Treatment is symptomatic and supportive.

STORAGE

Store below 25°C.

Protect from moisture and direct sunlight.

Keep in the original package.

SHELF LIFE

36 months.

PRESENTATION

Available strengths:

• WAPROBEN® 6 mg

• WAPROBEN® 20 mg

• WAPROBEN® 40 mg

Pack sizes:

• 10 tablets

• 30 tablets

• 60 tablets