WAPOMEP® Gastro-Resistant Tablets

Omeprazole Delayed-Release Tablets

For Veterinary Use Only

COMPOSITION

WAPOMEP® 10

Each gastro-resistant tablet contains:

Omeprazole ............................................. 10 mg

Excipients ............................................... q.s.

WAPOMEP® 20

Each gastro-resistant tablet contains:

Omeprazole ............................................. 20 mg

Excipients ............................................... q.s.

PHARMACEUTICAL FORM

Enteric-coated (gastro-resistant) tablets for oral administration.

TARGET SPECIES

• Dogs

• Cats

INDICATIONS

WAPOMEP® is indicated for the treatment and prevention of gastric acid-related disorders, including:

• Gastric ulcers

• Duodenal ulcers

• Gastritis

• Gastroesophageal reflux disease (GERD)

• Esophagitis

• NSAID-associated gastric ulceration

• Stress-related gastric ulceration

• Hyperacidity associated with systemic disease

It may also be used as part of combination therapy for gastric ulcer management and upper gastrointestinal disorders.

PHARMACOLOGICAL PROPERTIES

Omeprazole is a proton pump inhibitor (PPI).

It irreversibly inhibits the gastric H⁺/K⁺-ATPase enzyme (proton pump) in parietal cells, resulting in profound and prolonged suppression of gastric acid secretion.

Its acid-suppressive effect lasts approximately 24 hours following a single daily dose.

DOSAGE AND ADMINISTRATION

Administer orally.

Dogs

0.7–1.0 mg/kg body weight once daily

Cats

0.5–1.0 mg/kg body weight once daily

Treatment duration:

• Gastritis: 5–7 days

• Gastric ulcers: 14–28 days

• Chronic acid-related disease: According to veterinary assessment.

Administer preferably on an empty stomach.

Do not crush or split gastro-resistant tablets.

CONTRAINDICATIONS

Do not use in animals with known hypersensitivity to omeprazole or other proton pump inhibitors.

SPECIAL WARNINGS

Use with caution in animals with severe hepatic impairment.

Long-term therapy should be periodically reviewed by the attending veterinarian.

ADVERSE REACTIONS

Occasionally:

• Vomiting

• Diarrhea

• Flatulence

• Mild reduction in appetite

Rarely:

• Transient elevation of liver enzymes

• Hypersensitivity reactions

USE DURING PREGNANCY AND LACTATION

Use only according to the benefit-risk assessment of the attending veterinarian.

DRUG INTERACTIONS

Omeprazole may alter the absorption of drugs requiring an acidic gastric environment.

Use caution when administered with:

• Ketoconazole

• Itraconazole

• Iron preparations

• Clopidogrel (where applicable)

OVERDOSE

Overdosage is generally well tolerated but may result in:

• Gastrointestinal disturbances

• Lethargy

• Reduced appetite

Treatment is symptomatic and supportive.

STORAGE

Store below 25°C.

Protect from moisture and direct sunlight.

Keep in the original blister until use.

SHELF LIFE

36 months.

PRESENTATION

Available strengths:

• WAPOMEP® 10 mg

• WAPOMEP® 20 mg

Pack sizes:

• 10 tablets

• 30 tablets

• 100 tablets