WAPCLIN® Capsules

Clindamycin Hydrochloride Capsules

For Veterinary Use Only

COMPOSITION

WAPCLIN® 25

Each capsule contains:

Clindamycin Hydrochloride ................. 25 mg

Excipients .......................................... q.s.

WAPCLIN® 75

Each capsule contains:

Clindamycin Hydrochloride ................. 75 mg

Excipients .......................................... q.s.

WAPCLIN® 150

Each capsule contains:

Clindamycin Hydrochloride ............... 150 mg

Excipients .......................................... q.s.

WAPCLIN® 300

Each capsule contains:

Clindamycin Hydrochloride ............... 300 mg

Excipients .......................................... q.s.

PHARMACEUTICAL FORM

Hard gelatin capsules for oral administration.

TARGET SPECIES

• Dogs

• Cats

INDICATIONS

WAPCLIN® is indicated for the treatment of bacterial infections caused by microorganisms susceptible to clindamycin.

Recommended for the treatment of:

• Superficial pyoderma

• Deep pyoderma

• Skin abscesses

• Bite wounds

• Cellulitis

• Dental infections

• Periodontal disease

• Osteomyelitis

• Bone infections

• Soft tissue infections

In cats:

• Toxoplasmosis

• Dental infections

• Skin infections

Treatment should be based on bacterial culture and antimicrobial susceptibility testing whenever possible.

SPECTRUM OF ACTIVITY

Active against susceptible strains of:

• Staphylococcus pseudintermedius

• Staphylococcus aureus

• Streptococcus spp.

• Clostridium spp.

• Fusobacterium spp.

• Bacteroides spp.

• Actinomyces spp.

• Toxoplasma gondii

PHARMACOLOGICAL PROPERTIES

Clindamycin is a lincosamide antibiotic with primarily bacteriostatic activity.

It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Clindamycin achieves high concentrations in skin, bone, oral tissues, and abscesses, making it particularly useful for dermatological, dental, and musculoskeletal infections.

DOSAGE AND ADMINISTRATION

Administer orally.

Dogs

5.5–11 mg/kg body weight every 12 hours

or

11 mg/kg once daily

Treatment duration:

• Skin infections: 7–14 days

• Dental infections: 7–10 days

• Osteomyelitis: 21–28 days

Cats

11–12 mg/kg once daily

For toxoplasmosis:

10–12 mg/kg twice daily for 14–28 days, according to veterinary judgment.

CONTRAINDICATIONS

Do not use in animals with known hypersensitivity to clindamycin or lincomycin.

SPECIAL WARNINGS

Antimicrobial therapy should be guided by bacterial culture and susceptibility testing whenever possible.

Responsible antimicrobial use is recommended to minimize antimicrobial resistance.

ADVERSE REACTIONS

Occasionally:

• Vomiting

• Diarrhea

• Soft stools

• Reduced appetite

Rarely:

• Hypersensitivity reactions

USE DURING PREGNANCY AND LACTATION

Use only according to the benefit-risk assessment of the attending veterinarian.

DRUG INTERACTIONS

Avoid concurrent administration with:

• Erythromycin

• Chloramphenicol

• Macrolide antibiotics

These agents may antagonize the activity of clindamycin.

OVERDOSE

Overdosage may cause gastrointestinal disturbances.

Supportive therapy is recommended.

STORAGE

Store below 25°C.

Protect from moisture and direct sunlight.

Keep in the original package.

SHELF LIFE

36 months.

PRESENTATION

Available strengths:

• WAPCLIN® 25

• WAPCLIN® 75

• WAPCLIN® 150

• WAPCLIN® 300

Pack sizes:

• 10 capsules

• 20 capsules

• 100 capsules