ADEVIA® Injection

Vitamins A, D3 & E Injection

Sterile Oily Solution for Injection
100 mL

For Veterinary Use Only

COMPOSITION

Each 1 mL contains:

• Vitamin A Palmitate ............... 500,000 IU

• Vitamin D3 (Cholecalciferol) .... 75,000 IU

• Vitamin E (α-Tocopheryl Acetate) .... 50 mg

Excipients (Oily Vehicle) .............. q.s. to 1 mL

PHARMACEUTICAL FORM

Sterile oily solution for intramuscular or subcutaneous injection.

TARGET SPECIES

• Cattle

• Buffaloes

• Sheep

• Goats

• Camels

• Horses

• Swine

INDICATIONS

ADEVIA® is indicated for the prevention and treatment of Vitamin A, D3 and E deficiencies and as supportive therapy for:

• Vitamin deficiency syndromes

• Reduced fertility

• Delayed estrus

• Poor conception rates

• Embryonic loss associated with vitamin deficiencies

• Weak newborn animals

• Rickets

• Osteomalacia

• Poor growth

• Nutritional muscular degeneration

• Stress associated with transportation, vaccination and environmental changes

• Reduced immunity

• Recovery following disease

• Improvement of reproductive performance

PHARMACOLOGICAL PROPERTIES

Vitamin A

• Maintains epithelial integrity

• Supports vision

• Enhances immunity

• Improves reproductive performance

Vitamin D3

• Regulates calcium and phosphorus metabolism

• Promotes bone mineralization

• Supports skeletal development

Vitamin E

• Powerful antioxidant

• Protects muscle tissue

• Improves fertility

• Enhances immune response

• Reduces oxidative stress

The combination provides comprehensive support for growth, fertility, immunity and skeletal health.

DOSAGE AND ADMINISTRATION

Administer by deep intramuscular or subcutaneous injection.

Cattle & Buffaloes

5–10 mL

Horses & Camels

5–10 mL

Calves

2–5 mL

Sheep & Goats

2–3 mL

Lambs & Kids

1 mL

Swine

2–5 mL

Repeat after 2–4 weeks if necessary or according to veterinary advice.

CONTRAINDICATIONS

Do not administer to animals with known hypersensitivity to any component of the formulation.

Avoid excessive or repeated administration of fat-soluble vitamins.

SPECIAL WARNINGS

Do not inject intravenously.

Use sterile equipment.

Inject at different sites when administering large volumes.

ADVERSE REACTIONS

Occasionally:

• Mild swelling at the injection site

• Temporary discomfort

Rarely:

• Hypersensitivity reactions

USE DURING PREGNANCY AND LACTATION

May be administered during pregnancy and lactation according to veterinary recommendation.

Avoid excessive Vitamin A dosing during early pregnancy.

DRUG INTERACTIONS

Compatible with most antibiotics, mineral supplements and supportive therapies.

Do not mix with other injectable products in the same syringe.

OVERDOSE

Excessive administration may result in hypervitaminosis A or D.

Treatment should be symptomatic.

WITHDRAWAL PERIOD

Meat: Zero days*

Milk: Zero days*

*According to national registration requirements.

STORAGE

Store below 25°C.

Protect from direct sunlight.

Do not freeze.

Keep the vial in the original carton.

SHELF LIFE

• 36 months before opening.

• Use within 28 days after first broaching (subject to stability validation).

PRESENTATION

• 50 mL vial

• 100 mL vial

• 250 mL vial